Melanotan-2 (MT-2) is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). Its cyclic structure and D-phenylalanine + norleucine substitutions confer significantly greater proteolytic stability and receptor affinity than the linear endogenous α-MSH parent peptide. Structurally, MT-2 is the parent research compound from which the shorter cyclic heptapeptide PT-141 (Bremelanotide) was later derived, and both remain persistent tool compounds in the melanocortin-receptor pharmacology literature.

ProSource Labs supplies Melanotan-2 in the following available vial sizes: 10mg. Each Melanotan-2 vial contains pure lyophilized peptide — no fillers, no bulking agents. Product SKU references: MT2-10MV10MG.

• Peptide class: Cyclic 7-amino-acid melanocortin receptor agonist
• Residue count: 7 amino acids
• Molecular weight: ~1,024 Da
• Cyclic 7-amino-acid α-MSH analog; MW ~1,024 Da
• Parent research compound of the shorter PT-141 (Bremelanotide)
• Non-selective pan-melanocortin receptor agonist (MC1R–MC5R)
• Cyclic + D-amino-acid substitutions confer improved proteolytic stability vs α-MSH

Batches are characterized by ESI mass spectrometry to confirm molecular weight against the theoretical value, with amino-acid sequence confirmation on selected QA lots. Peptide content assay distinguishes net peptide mass from residual counter-ion salt.

Lyophilized Melanotan-2 vials should be stored at -20°C (or colder) in a laboratory freezer, inside the sealed factory container. Minimize warm-up cycles — move only the specific vial needed for a given experiment out of frozen storage at a time.

All laboratory handling of Melanotan-2 should follow the receiving institution's SOPs and applicable peer-reviewed protocols relevant to the researcher's specific experimental question. ProSource Labs does not publish end-user preparation or usage instructions.

Every batch of Melanotan-2 released by ProSource Labs undergoes independent reverse-phase High Performance Liquid Chromatography (HPLC) — the industry-standard analytical method for this class of research compound. Target chromatographic purity is typically ≥ 99%.

Additional characterization may include ESI mass spectrometry for molecular weight confirmation, Karl Fischer titration for residual moisture, and appearance/solubility inspection. A batch-specific Certificate of Analysis (COA) is available on request through customer support after purchase.

Each production lot of Melanotan-2 is quarantined pending analytical release, tested against documented purity, identity, and moisture acceptance criteria, and only released to sellable inventory after passing every QA checkpoint. Batches that fail any single criterion are quarantined and never reach customer-facing inventory.

If a vial of Melanotan-2 you received from ProSource Labs ever fails your own institution's incoming QA testing, contact customer support at support@prosourcelabs.org — we retain samples of every batch for cross-verification.

Melanotan-2 is used in preclinical rodent and cell-culture research on melanocortin receptor pharmacology across the full MC1R–MC5R subtype family — with the most extensively characterized preclinical work in MC1R (melanogenesis), MC3R and MC4R (central appetite, energy homeostasis, and sexual-behavior circuits), and MC5R (peripheral exocrine function). Published preclinical literature has examined MT-2 effects on hypothalamic feeding circuits, thermoregulation, and MC1R-driven pigmentation biology in rodent and cell-culture models. Its non-selective pan-MC receptor engagement makes it a useful comparator to more receptor-selective melanocortin research peptides.

Melanotan-2 vials ship in tamper-evident, moisture-resistant, cold-chain-friendly outer packaging from our Southern California distribution facility for fast US domestic delivery — typically 2-4 business days coast-to-coast, with expedited options available at checkout.

Every Melanotan-2 shipment is discreet — the outer packaging carries no product-specific branding or direct reference to the compound name inside, protecting researcher privacy. Tracking numbers are emailed automatically. For institutional or high-volume orders, dedicated wholesale pricing is available through the wholesale portal.